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  • Moon, H., Zheng, X., Loh, T., Jang, H., Liu, Y., Jung, D., Williams, D. and Shen, H. (2017). Effects of PTCs on nonsense‑mediated mRNA decay are dependent on PTC location. Oncology Letters.
    http://dx.doi.org/10.3892/ol.2017.5627

  • Loh, T., Choi, N., Moon, H., Jang, H., Liu, Y., Zhou, J., Zheng, X. and Shen, H. (2017). Suppression of 5′ splice-sites through multiple exonic motifs by hnRNP L. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1860(3), pp.363-373.
    http://dx.doi.org/10.1016/j.bbagrm.2017.01.010

  • Loh, T., Moon, H., Jang, H., Liu, Y., Choi, N., Shen, S., Williams, D., Jung, D., Zheng, X. and Shen, H. (2016). SR proteins regulate V6exon splicing of CD44 pre-mRNA. BMB Reports, 49(11), pp.612-616.
    http://dx.doi.org/10.5483/bmbrep.2016.49.11.118

  • Zheng, X., Cho, S., Moon, H., Loh, T., Jang, H. and Shen, H. (2016). Detecting RNA–Protein Interaction Using End-Labeled Biotinylated RNA Oligonucleotides and Immunoblotting. Methods in Molecular Biology, pp.35-44.
    http://dx.doi.org/10.1007/978-1-4939-3591-8_4

  • Moon, H., Zheng, X., Loh, T., Jang, H., Liu, Y., Jung, D., Williams, D. and Shen, H. (2015). Identification of Regulatory-RNAs for Alternative Splicing of Ron Proto-Oncogene. Journal of Cancer, 6(12), pp.1346-1351.
    http://dx.doi.org/10.7150/jca.13361

  • Cho, S., Moon, H., Loh, T., Jang, H., Liu, Y., Zhou, J., Ohn, T., Zheng, X. and Shen, H. (2015). Splicing inhibition of U2AF 65 leads to alternative exon skipping. Proceedings of the National Academy of Sciences, 112(32), pp.9926-9931.
    http://dx.doi.org/10.1073/pnas.1500639112

  • Loh, T., Moon, H., Cho, S., Jang, H., Liu, Y., Tai, H., Jung, D., Williams, D., Kim, H., Shin, M., Liao, D., Zhou, J., Shi, W., Zheng, X. and Shen, H. (2015). CD44 alternative splicing and hnRNP A1 expression are associated with the metastasis of breast cancer. Oncology Reports.
    http://dx.doi.org/10.3892/or.2015.4110

  • Loh, T., Cho, S., Moon, H., Jang, H., Williams, D., Jung, D., Kim, I., Ghigna, C., Biamonti, G., Zheng, X. and Shen, H. (2015). hnRNP L inhibits CD44 V10 exon splicing through interacting with its upstream intron. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1849(6), pp.743-750.
    http://dx.doi.org/10.1016/j.bbagrm.2015.01.004

  • Moon, H., Cho, S., Loh, T., Oh, H., Jang, H., Zhou, J., Kwon, Y., Liao, D., Jun, Y., Eom, S., Ghigna, C., Biamonti, G., Green, M., Zheng, X. and Shen, H. (2014). SRSF2 promotes splicing and transcription of exon 11 included isoform in Ron proto-oncogene. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1839(11), pp.1132-1140.
    http://dx.doi.org/10.1016/j.bbagrm.2014.09.003

  • Cho, S., Moon, H., Loh, T., Oh, H., Williams, D., Liao, D., Zhou, J., Green, M., Zheng, X. and Shen, H. (2014). PSF contacts exon 7 of SMN2 pre-mRNA to promote exon 7 inclusion. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1839(6), pp.517-525.
    http://dx.doi.org/10.1016/j.bbagrm.2014.03.003

  • Zheng, X., Cho, S., Moon, H., Loh, T., Oh, H., Green, M. and Shen, H. (2014). Polypyrimidine tract binding protein inhibits IgM pre-mRNA splicing by diverting U2 snRNA base-pairing away from the branch point. RNA, 20(4), pp.440-446.
    http://dx.doi.org/10.1261/rna.043737.113

  • Cho, S., Moon, H., Loh, T., Oh, H., Cho, S., Choy, H., Song, W., Chun, J., Zheng, X. and Shen, H. (2014). hnRNP M facilitates exon 7 inclusion of SMN2 pre-mRNA in spinal muscular atrophy by targeting an enhancer on exon 7. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1839(4), pp.306-315.
    http://dx.doi.org/10.1016/j.bbagrm.2014.02.006

  • Jang, H., Lee, M., Loh, T., Choi, S., Oh, H., Moon, H., Cho, S., Hong, S., Kim, D., Sheng, Z., Green, M., Park, D., Zheng, X. and Shen, H. (2014). Exon 9 skipping of apoptotic caspase-2 pre-mRNA is promoted by SRSF3 through interaction with exon 8. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1839(1), pp.25-32.
    http://dx.doi.org/10.1016/j.bbagrm.2013.11.006

  • Cho, S., Moon, H., Loh, T., Oh, H., Kim, H., Shin, M., Liao, D., Zhou, J., Zheng, X. and Shen, H. (2014). 3′ Splice Site Sequences of Spinal Muscular Atrophy Related SMN2 Pre-mRNA Include Enhancers for Nearby Exons. The Scientific World Journal, 2014, pp.1-9.
    http://dx.doi.org/10.1155/2014/617842

  • Yang, X., Shen, H., Gao, X., Zheng, X., Qin, R. and Zhou, J. (2013). Predominant expression of exon 7 skipped SMN mRNAs in lung based on analysis of transcriptome sequencing datasets. Neurological Sciences, 35(3), pp.391-396.
    http://dx.doi.org/10.1007/s10072-013-1524-4

  • Loh, T., Moon, H., Cho, S., Jung, D., Hong, S., Kim, D., Green, M., Zheng, X., Zhou, J. and Shen, H. (2013). SC35 promotes splicing of the C5-V6-C6 isoform of CD44 pre-mRNA. Oncology Reports.
    http://dx.doi.org/10.3892/or.2013.2812

  • E., Z., Wang, L., Qin, R., Shen, H. and Zhou, J. (2014). Genome-Wide Characterisation of Gene Expression in Rice Leaf Blades at 25°C and 30°C. The Scientific World Journal, 2014, pp.1-7.
    http://dx.doi.org/10.1155/2014/917292

  • Moon, H., Cho, S., Loh, T., Zhou, J., Ghigna, C., Biamonti, G., Green, M., Zheng, X. and Shen, H. (2013). A 2-nt RNA enhancer on exon 11 promotes exon 11 inclusion of the Ron proto-oncogene. Oncology Reports.
    http://dx.doi.org/10.3892/or.2013.2835

  • Oh, H., Lee, E., Jang, H., Lee, J., Moon, H., Sheng, Z., Jun, Y., Loh, T., Cho, S., Zhou, J., Green, M., Zheng, X. and Shen, H. (2013). hnRNP A1 contacts exon 5 to promote exon 6 inclusion of apoptotic Fas gene. Apoptosis, 18(7), pp.825-835.
    http://dx.doi.org/10.1007/s10495-013-0824-8

  • Moon, H., Cho, S., Yang, X., Zhou, J., Loh, T., Zheng, X. and Shen, H. (2012). Identification of novel splicing variants from RON proto-oncogene pre-mRNA. Oncology Reports.
    http://dx.doi.org/10.1007/s10495-013-0824-8

  • Cho, S., Moon, H., Yang, X., Zhou, J., Kim, H., Shin, M., Loh, T., Zheng, X. and Shen, H. (2012). Validation of trans-acting elements that promote exon 7 skipping of SMN2 in SMN2-GFP stable cell line. Biochemical and Biophysical Research Communications, 423(3), pp.531-535.
    http://dx.doi.org/10.1016/j.bbrc.2012.05.161

  • Lee, J., Zhou, J., Zheng, X., Cho, S., Moon, H., Loh, T., Jo, K. and Shen, H. (2012). Identification of a novel cis-element that regulates alternative splicing of Bcl-x pre-mRNA. Biochemical and Biophysical Research Communications, 420(2), pp.467-472.
    http://dx.doi.org/10.1016/j.bbrc.2012.03.029.

  • Shen, H., Zheng, X., Luecke, S. and Green, M. (2010). The U2AF35-related protein Urp contacts the 3' splice site to promote U12-type intron splicing and the second step of U2-type intron splicing. Genes & Development, 24(21), pp.2389-2394.
    http://dx.doi.org/10.1101/gad.1974810.

  • Jenkins, J., Shen, H., Green, M. and Kielkopf, C. (2008). Solution Conformation and Thermodynamic Characteristics of RNA Binding by the Splicing Factor U2AF65. Journal of Biological Chemistry, 283(48), pp.33641-33649.
    http://dx.doi.org/10.1074/jbc.M806297200.

  • Shen, H., Zheng, X., Shen, J., Zhang, L., Zhao, R. and Green, M. (2008). Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome. Genes & Development, 22(13), pp.1796-1803.
    http://dx.doi.org/10.1101/gad.1657308.

  • Garifulin, O., Qi, Z., Shen, H., Patnala, S., Green, M. and Boyartchuk, V. (2007). Irf3 Polymorphism Alters Induction of Interferon Beta in Response to Listeria monocytogenes Infection. PLoS Genetics, 3(9), p.e152.
    http://dx.doi.org/10.1371/journal.pgen.0030152

  • Shen, H. and Green, M. (2007). RS domain–splicing signal interactions in splicing of U12-type and U2-type introns. Nat Struct Mol Biol, 14(7), pp.597-603.
    http://dx.doi.org/10.1038/nsmb1263

  • Shen, H. (2006). RS domains contact splicing signalsand promote splicing by a common mechanism in yeast through humans. Genes & Development, 20(13), pp.1755-1765.
    http://dx.doi.org/10.1101/gad.1422106

  • Sickmier, E., Frato, K., Shen, H., Paranawithana, S., Green, M. and Kielkopf, C. (2006). Structural Basis for Polypyrimidine Tract Recognition by the Essential Pre-mRNA Splicing Factor U2AF65. Molecular Cell, 23(1), pp.49-59.
    http://dx.doi.org/10.1016/j.molcel.2006.05.025

  • Ghigna, C., Giordano, S., Shen, H., Benvenuto, F., Castiglioni, F., Comoglio, P., Green, M., Riva, S. and Biamonti, G. (2005). Cell Motility Is Controlled by SF2/ASF through Alternative Splicing of the Ron Protooncogene. Molecular Cell, 20(6), pp.881-890.
    http://dx.doi.org/10.1016/j.molcel.2005.10.026

  • Shen, H. and Green, M. (2004). A Pathway of Sequential Arginine-Serine-Rich Domain-Splicing Signal Interactions during Mammalian Spliceosome Assembly. Molecular Cell, 16(3), pp.363-373.
    http://dx.doi.org/10.1016/j.molcel.2004.10.021

  • Shen, H., Kan, J. and Green, M. (2004). Arginine-Serine-Rich Domains Bound at Splicing Enhancers Contact the Branchpoint to Promote Prespliceosome Assembly. Molecular Cell, 13(3), pp.367-376.
    http://dx.doi.org/10.1016/S1097-2765(04)00025-5

  • Shen, H., Kan, J., Ghigna, C., Biamonti, G. and Green, M. (2004). A single polypyrimidine tract binding protein (PTB) binding site mediates splicing inhibition at mouse IgM exons M1 and M2. RNA, 10(5), pp.787-794.
    http://dx.doi.org/10.1261/rna.5229704

  • Shen, H. and Kang, C. (2000). Two Site Contact of Elongating Transcripts to Phage T7 RNA Polymerase at C-terminal Regions. Journal of Biological Chemistry, 276(6), pp.4080-4084.
    http://dx.doi.org/10.1074/jbc.M008616200

 

 

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